LC-MS metabolomics by application of HILIC


Hydrophilic interaction chromatography (HILIC) is a powerful method for separation of polar compounds. MS-Omics is recommending HILIC chromatography to complement GC-MS analysis. HILIC can measure a wide range of polar metabolites and is especially valuable for detection of:


Nucleocompounds - Phosphorylated compounds - Water soluble vitamins


MS-Omics is using Waters qTOF instruments for HILIC applications and our method is based on:



For a detailed review on HILIC and the many potential applications we recommend this review: